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Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes
The worldwide prevalence of type 2 diabetes (T2D) is increasing. Despite normal to higher bone density, patients with T2D paradoxically have elevated fracture risk resulting, in part, from poor bone quality. Advanced glycation endproducts (AGEs) and inflammation as a consequence of enhanced receptor...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7253018/ https://ncbi.nlm.nih.gov/pubmed/32267250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135236 |
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