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Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes

Diabetes is the leading cause of end-stage renal disease worldwide. Our understanding of the early kidney response to chronic hyperglycemia remains incomplete. To address this, we first investigated the urinary proteomes of otherwise healthy youths with and without type 1 diabetes and subsequently e...

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Publicat a:PLoS One
Autors principals: Van, Julie A. D., Clotet-Freixas, Sergi, Hauschild, Anne-Christin, Batruch, Ihor, Jurisica, Igor, Elia, Yesmino, Mahmud, Farid H., Sochett, Etienne, Diamandis, Eleftherios P., Scholey, James W., Konvalinka, Ana
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250451/
https://ncbi.nlm.nih.gov/pubmed/32453760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233639
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