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Urinary proteomics links keratan sulfate degradation and lysosomal enzymes to early type 1 diabetes

Diabetes is the leading cause of end-stage renal disease worldwide. Our understanding of the early kidney response to chronic hyperglycemia remains incomplete. To address this, we first investigated the urinary proteomes of otherwise healthy youths with and without type 1 diabetes and subsequently e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Van, Julie A. D., Clotet-Freixas, Sergi, Hauschild, Anne-Christin, Batruch, Ihor, Jurisica, Igor, Elia, Yesmino, Mahmud, Farid H., Sochett, Etienne, Diamandis, Eleftherios P., Scholey, James W., Konvalinka, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250451/
https://ncbi.nlm.nih.gov/pubmed/32453760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233639
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