Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes

Mice deficient in the transcription factor Runx3 develop a multitude of immune system defects, including early onset colitis. This paper demonstrates that Runx3 is expressed in colonic mononuclear phagocytes (MNP), including resident macrophages (RM) and dendritic cell subsets (cDC2). Runx3 deletion...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Hantisteanu, Shay, Dicken, Yosef, Negreanu, Varda, Goldenberg, Dalia, Brenner, Ori, Leshkowitz, Dena, Lotem, Joseph, Levanon, Ditsa, Groner, Yoram
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250423/
https://ncbi.nlm.nih.gov/pubmed/32453801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233044
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