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Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells

SUMMARY: Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge fac...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: El-Gammal, Zaynab, AlOkda, Abdelrahman, Ali, Sameh S., Reda, Asmaa, Magdeldin, Sameh, Mansour, Ragaa, El-Badri, Nagwa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250418/
https://ncbi.nlm.nih.gov/pubmed/32453737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232759
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