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Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells

SUMMARY: Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge fac...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: El-Gammal, Zaynab, AlOkda, Abdelrahman, Ali, Sameh S., Reda, Asmaa, Magdeldin, Sameh, Mansour, Ragaa, El-Badri, Nagwa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250418/
https://ncbi.nlm.nih.gov/pubmed/32453737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232759
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