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Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells

SUMMARY: Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge fac...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: El-Gammal, Zaynab, AlOkda, Abdelrahman, Ali, Sameh S., Reda, Asmaa, Magdeldin, Sameh, Mansour, Ragaa, El-Badri, Nagwa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250418/
https://ncbi.nlm.nih.gov/pubmed/32453737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232759
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