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Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells

SUMMARY: Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge fac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: El-Gammal, Zaynab, AlOkda, Abdelrahman, Ali, Sameh S., Reda, Asmaa, Magdeldin, Sameh, Mansour, Ragaa, El-Badri, Nagwa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250418/
https://ncbi.nlm.nih.gov/pubmed/32453737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232759
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