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Analysis of responder-based endpoints: improving power through utilising continuous components

BACKGROUND: Clinical trials and other studies commonly assess the effectiveness of an intervention through the use of responder-based endpoints. These classify patients based on whether they meet a number of criteria which often involve continuous variables categorised as being above or below a thre...

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Pubblicato in:Trials
Autori principali: Wason, James, McMenamin, Martina, Dodd, Susanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7249409/
https://ncbi.nlm.nih.gov/pubmed/32450909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04353-8
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