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Ginsenoside metabolite 20(S)-protopanaxadiol promotes neural stem cell transition from a state of proliferation to differentiation by inducing autophagy and cell cycle arrest

20(S)-Protopanaxadiol (PPD) is an active ginseng metabolite and is the final form of protopanaxadiol saponins metabolized by human intestinal microflora. The neuroprotective effects and mechanisms underlying PPD on neural stem cells (NSCs) are not completely understood. The aim of the present study...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Chen, Shali, He, Ji, Qin, Xiyuan, Luo, Tiao, Pandey, Aparna, Li, Jijia, Liu, Suyou, Luo, Junli, Wang, Qi, Luo, Zhiyong
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248512/
https://ncbi.nlm.nih.gov/pubmed/32319663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11081
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