Ginsenoside metabolite 20(S)-protopanaxadiol promotes neural stem cell transition from a state of proliferation to differentiation by inducing autophagy and cell cycle arrest

20(S)-Protopanaxadiol (PPD) is an active ginseng metabolite and is the final form of protopanaxadiol saponins metabolized by human intestinal microflora. The neuroprotective effects and mechanisms underlying PPD on neural stem cells (NSCs) are not completely understood. The aim of the present study...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Chen, Shali, He, Ji, Qin, Xiyuan, Luo, Tiao, Pandey, Aparna, Li, Jijia, Liu, Suyou, Luo, Junli, Wang, Qi, Luo, Zhiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248512/
https://ncbi.nlm.nih.gov/pubmed/32319663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11081
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