The Ginsenoside 20-O-β-D-Glucopyranosyl-20(S)-Protopanaxadiol Induces Autophagy and Apoptosis in Human Melanoma via AMPK/JNK Phosphorylation

Studies have shown that a major metabolite of the red ginseng ginsenoside Rb1, called 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (GPD), exhibits anticancer properties. However, the chemotherapeutic effects and molecular mechanisms behind GPD action in human melanoma have not been previously inves...

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Detalhes bibliográficos
Main Authors: Kang, Soouk, Kim, Jong-Eun, Song, Nu Ry, Jung, Sung Keun, Lee, Mee Hyun, Park, Jun Seong, Yeom, Myeong-Hun, Bode, Ann M., Dong, Zigang, Lee, Ki Won
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138097/
https://ncbi.nlm.nih.gov/pubmed/25137374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104305
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