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Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion

Ischemia heart disease is the leading cause of death world-widely and has increased prevalence and exacerbated myocardial infarction with aging. Sestrin2, a stress-inducible protein, declines with aging in the heart and the rescue of Sestrin2 in the aged mouse heart improves the resistance to ischem...

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Publicat a:Redox Biol
Autors principals: Ren, Di, Quan, Nanhu, Fedorova, Julia, Zhang, Jingwen, He, Zhibin, Li, Ji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248240/
https://ncbi.nlm.nih.gov/pubmed/32447260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101556
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