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Sestrin2 modulates cardiac inflammatory response through maintaining redox homeostasis during ischemia and reperfusion

Ischemia heart disease is the leading cause of death world-widely and has increased prevalence and exacerbated myocardial infarction with aging. Sestrin2, a stress-inducible protein, declines with aging in the heart and the rescue of Sestrin2 in the aged mouse heart improves the resistance to ischem...

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Библиографические подробности
Главные авторы: Di Ren, Nanhu Quan, Julia Fedorova, Jingwen Zhang, Zhibin He, Ji Li
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020-07-01
Серии:Redox Biology
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Online-ссылка:http://www.sciencedirect.com/science/article/pii/S221323172030481X
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