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Structural basis of the interplay between α-synuclein and Tau in regulating pathological amyloid aggregation

Amyloid aggregation of pathological proteins is closely associated with a variety of neurodegenerative diseases, and α-synuclein (α-syn) deposition and Tau tangles are considered hallmarks of Parkinson's disease and Alzheimer's disease, respectively. Intriguingly, α-syn and Tau have been f...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Lu, Jinxia, Zhang, Shengnan, Ma, Xiaojuan, Jia, Chunyu, Liu, Zhenying, Huang, Chengan, Liu, Cong, Li, Dan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247300/
https://ncbi.nlm.nih.gov/pubmed/32291284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012284
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