Structural basis of the interplay between α-synuclein and Tau in regulating pathological amyloid aggregation

Amyloid aggregation of pathological proteins is closely associated with a variety of neurodegenerative diseases, and α-synuclein (α-syn) deposition and Tau tangles are considered hallmarks of Parkinson's disease and Alzheimer's disease, respectively. Intriguingly, α-syn and Tau have been f...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Lu, Jinxia, Zhang, Shengnan, Ma, Xiaojuan, Jia, Chunyu, Liu, Zhenying, Huang, Chengan, Liu, Cong, Li, Dan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247300/
https://ncbi.nlm.nih.gov/pubmed/32291284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012284
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