Different Heat Shock Proteins Bind α-Synuclein With Distinct Mechanisms and Synergistically Prevent Its Amyloid Aggregation

α-Synuclein (α-Syn) forms pathological amyloid aggregates deposited in Lewy bodies and Lewy neurites in the brain of Parkinson’s disease (PD) patients. Heat shock proteins (Hsps) are the major components of the cellular chaperone network, which are responsible for preventing proteins from amyloid ag...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Front Neurosci
Autores principales: Jia, Chunyu, Ma, Xiaojuan, Liu, Zhenying, Gu, Jinge, Zhang, Xiang, Li, Dan, Zhang, Shengnan
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842937/
https://ncbi.nlm.nih.gov/pubmed/31749672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.01124
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares