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Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy
α-Synuclein (α-syn) amyloid fibrils are the major component of Lewy bodies, which are the pathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. High-resolution structure of α-syn fibril is important for understanding its assembly and pathological mechanism. Here, we determin...
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| Publicat a: | Cell Res |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123497/ https://ncbi.nlm.nih.gov/pubmed/30065316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0075-x |
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