Amyloid fibril structure of α-synuclein determined by cryo-electron microscopy

α-Synuclein (α-syn) amyloid fibrils are the major component of Lewy bodies, which are the pathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. High-resolution structure of α-syn fibril is important for understanding its assembly and pathological mechanism. Here, we determin...

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Udgivet i:Cell Res
Main Authors: Li, Yaowang, Zhao, Chunyu, Luo, Feng, Liu, Zhenying, Gui, Xinrui, Luo, Zhipu, Zhang, Xiang, Li, Dan, Liu, Cong, Li, Xueming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123497/
https://ncbi.nlm.nih.gov/pubmed/30065316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0075-x
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