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The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62

p62/sequestosome-1 is a scaffolding protein involved in diverse cellular processes such as autophagy, oxidative stress, cell survival and death. It has been identified to interact with atypical protein kinase Cs (aPKCs), linking these kinases to NF-κB activation by tumor necrosis factor α (TNFα). Th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ha, Jihoon, Kim, Minbeom, Seo, Dongyeob, Park, Jin Seok, Lee, Jaewon, Lee, Jinjoo, Park, Seok Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247158/
https://ncbi.nlm.nih.gov/pubmed/32354117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21093116
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