USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO

DNA damage-induced activation of the transcription factor NF-κB plays an important role in the cellular response to genotoxic stress. However, uncontrolled NF-κB activation upon DNA damage may lead to deleterious consequences. Although the mechanisms mediating genotoxic NF-κB activation have been el...

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Main Authors: Niu, Jixiao, Shi, Yuling, Xue, Jingyan, Miao, Ruidong, Huang, Shengping, Wang, Tianyi, Wu, Jiong, Fu, Mingui, Wu, Zhao-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981146/
https://ncbi.nlm.nih.gov/pubmed/24270572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.247
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