تحميل...
Structure-based screening of chemical libraries to identify small molecules that are likely to bind with the SET and RING-associated (SRA) domain of Ubiquitin-like, PHD and Ring Finger-containing 1 (UHRF1)
OBJECTIVES: UHRF1 is a multi-domain protein that recognizes both histone and DNA modification marks on chromatin. UHRF1 is involved in various cellular processes that lead to tumorigenesis and thus attracted considerable attention as a potential anti-cancer drug target. The SRA domain is a unique to...
محفوظ في:
| الحاوية / القاعدة: | BMC Res Notes |
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| المؤلف الرئيسي: | |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BioMed Central
2020
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247125/ https://ncbi.nlm.nih.gov/pubmed/32448288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05103-4 |
| الوسوم: |
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