The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence

As senescence develops, cells sequentially acquire diverse senescent phenotypes along with simultaneous multistage gene reprogramming. It remains unclear what acts as the key regulator of the collective changes in gene expression at initiation of senescent reprogramming. Here we analyzed time series...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Jung, Hyun-Jung, Byun, Hae-Ok, Jee, Byul A., Min, Seongki, Jeoun, Un-woo, Lee, Young-Kyoung, Seo, Yonghak, Woo, Hyun Goo, Yoon, Gyesoon
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5339756/
https://ncbi.nlm.nih.gov/pubmed/28100769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.750539
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