Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction

Aims: Redox homeostasis is tightly controlled and regulates key cellular signaling pathways. The cell's antioxidant response provides a natural defense against oxidative stress, but excessive antioxidant generation leads to reductive stress (RS). This study elucidated how chronic RS, caused by...

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Bibliographic Details
Published in:Antioxid Redox Signal
Main Authors: Shanmugam, Gobinath, Wang, Ding, Gounder, Sellamuthu S., Fernandes, Jolyn, Litovsky, Silvio H., Whitehead, Kevin, Radhakrishnan, Rajesh Kumar, Franklin, Sarah, Hoidal, John R., Kensler, Thomas W., Dell'Italia, Louis, Darley-Usmar, Victor, Abel, E. Dale, Jones, Dean P., Ping, Peipei, Rajasekaran, Namakkal S.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc., publishers 2020
Subjects:
Forum Original Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247052/
https://ncbi.nlm.nih.gov/pubmed/32064894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2019.7808
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