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Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice

Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2/Nrf2) is an inducible transcription factor that is essential for maintenance of redox signaling in response to stress. This suggests that if Nrf2 expression response could be enhanced for a defined physiological pro-oxidant stress then it would be...

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Detalhes bibliográficos
Main Authors: Gobinath Shanmugam, Anil Kumar Challa, Silvio H. Litovsky, Asokan Devarajan, Ding Wang, Dean P. Jones, Victor M. Darley-Usmar, Namakkal Soorappan Rajasekaran
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019-10-01
Colecção:Redox Biology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231719304070
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