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Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice

BACKGROUND: Nuclear Factor Erythroid-derived 2-like 2 (Nrf2) senses oxidative environments and/or stress and initiates a cytoprotective response through transcriptional activation of antioxidant and detoxification genes. Several preclinical studies suggest that Nrf2 combats oxidative stress underlyi...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Quiles, Justin M., Narasimhan, Madhusudhanan, Shanmugam, Gobinath, Milash, Brett, Hoidal, John R., Rajasekaran, Namakkal S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496330/
https://ncbi.nlm.nih.gov/pubmed/28673258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3875-3
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