Disruption of nuclear factor (erythroid-derived-2)–like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle

Recently we have reported that age-dependent decline in antioxidant levels accelerated apoptosis and skeletal muscle degeneration. Here, we demonstrate genetic ablation of the master cytoprotective transcription factor, nuclear factor (erythroid-derived-2)–like 2 (Nrf2), aggravates cardiotoxin (CTX)...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Shelar, Sandeep Balu, Narasimhan, Madhusudhanan, Shanmugam, Gobinath, Litovsky, Silvio Hector, Gounder, Sellamuthu S., Karan, Goutam, Arulvasu, Cinnasamy, Kensler, Thomas W., Hoidal, John R., Darley-Usmar, Victor M., Rajasekaran, Namakkal S.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836373/
https://ncbi.nlm.nih.gov/pubmed/26839378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500153
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