Detection of Alzheimer’s Disease Pathology in patients using biochemical biomarkers: prospects and challenges for use in clinical practice.

BACKGROUND: Amyloid-β1-42 peptide was identified 34 years ago in amyloid plaques obtained from Alzheimer’s disease (AD) and Down’s Syndrome patients’ autopsied brain tissue. This led to development of immunoassay methods for measuring this marker of amyloid plaque burden in cerebrospinal fluid (CSF)...

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Bibliografische gegevens
Gepubliceerd in:J Appl Lab Med
Hoofdauteurs: Shaw, Leslie M, Korecka, Magdalena, Figurski, Michal, Toledo, Jon, Irwin, David, Kang, Ju Hee, Trojanowski, John Q
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7246169/
https://ncbi.nlm.nih.gov/pubmed/31848218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/jalm.2019.029587
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