Qualification of a Surrogate Matrix-Based Absolute Quantification Method for Amyloid-β(42) in Human Cerebrospinal Fluid Using 2D UPLC-Tandem Mass Spectrometry

The primary aims of this work were to: 1) establish a calibrator surrogate matrix for quantification of amyloid-β (Aβ)(42) in human cerebrospinal fluid (CSF) and preparation of quality control samples for LC-MS-MS methodology, 2) validate analytical performance of the assay, and 3) evaluate its diag...

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Autores principales: Korecka, Magdalena, Waligorska, Teresa, Figurski, Michal, Toledo, Jon B., Arnold, Steven E., Grossman, Murray, Trojanowski, John Q., Shaw, Leslie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159707/
https://ncbi.nlm.nih.gov/pubmed/24625802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-132489
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