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Clinical Utility and Analytical Challenges in Measurement of Cerebrospinal Fluid Amyloid-β(1–42) and τ Proteins as Alzheimer Disease Biomarkers
BACKGROUND: Over the past 2 decades, clinical studies have provided evidence that cerebrospinal fluid (CSF) amyloid β(1–42) (Aβ(1–42)), total τ(t-τ), and τ phosphorylated at Thr181 (p-τ(181)) are reliable biochemical markers of Alzheimer disease (AD) neuropathology. CONTENT: In this review, we summa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159709/ https://ncbi.nlm.nih.gov/pubmed/23519967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2013.202937 |
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