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UPLC-Tandem Mass Spectrometry for Quantification of Busulfan in Human Plasma: Application to Therapeutic Drug Monitoring

Busulfan (Bu) is an alkylating agent commonly used in preparative regimens for hematologic malignant and non-malignant patients undergoing hematopoietic stem cell transplantation (HSCT). The objective of the present study was to develop an UPLC-MS/MS method for quantification of Bu in human plasma....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matar, Kamal M., Alshemmari, Salem H., Refaat, Samar, Anwar, Alia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265561/
https://ncbi.nlm.nih.gov/pubmed/32488110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65919-9
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