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Quantification of sunitinib in human plasma by high-performance liquid chromatography-tandem mass spectrometry

A rapid, sensitive and specific method was developed and validated using LC/MS/MS for determination of sunitinib in human plasma. Sample preparation involved a liquid-liquid extraction by the addition of 0.2 mL of plasma with 4.0 mL tert-butyl-methyl-ether extraction solution containing 25 ng/mL of...

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Detalhes bibliográficos
Main Authors: Minkin, Patton, Zhao, Ming, Chen, Zhaoyuan, Ouwerkerk, Jan, Gelderblom, Hans, Baker, Sharyn D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612784/
https://ncbi.nlm.nih.gov/pubmed/18823825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2008.09.007
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