Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry

BACKGROUND: Busulfan, an alkylating agent administered prior to hematopoietic stem cell transplantation, has a narrow therapeutic range and wide variability in metabolism. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for rapid and accurate quantification of plasma...

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Autors principals: Moon, Soo Young, Lim, Min Kyoo, Hong, Susie, Jeon, Yongbum, Han, Minje, Song, Sang Hoon, Lim, Kyoung Soo, Yu, Kyung-Sang, Jang, In-Jin, Lee, Ji Won, Kang, Hyoung Jin, Song, Junghan
Format: Artigo
Idioma:Inglês
Publicat: The Korean Society for Laboratory Medicine 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885779/
https://ncbi.nlm.nih.gov/pubmed/24422189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3343/alm.2014.34.1.7
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