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Detection of Alzheimer’s Disease Pathology in patients using biochemical biomarkers: prospects and challenges for use in clinical practice.
BACKGROUND: Amyloid-β1-42 peptide was identified 34 years ago in amyloid plaques obtained from Alzheimer’s disease (AD) and Down’s Syndrome patients’ autopsied brain tissue. This led to development of immunoassay methods for measuring this marker of amyloid plaque burden in cerebrospinal fluid (CSF)...
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| Pubblicato in: | J Appl Lab Med |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7246169/ https://ncbi.nlm.nih.gov/pubmed/31848218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/jalm.2019.029587 |
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