Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy

Resistance of acute myeloid leukemia (AML) to therapeutic agents is frequent. Consequently, the mechanisms leading to this resistance must be understood and addressed. In this paper, we demonstrate that inhibition of deubiquitinylase USP7 significantly reduces cell proliferation in vitro and in vivo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Leukemia
Autori principali: Cartel, Maëlle, Mouchel, Pierre-Luc, Gotanègre, Mathilde, David, Laure, Bertoli, Sarah, Mansat-De Mas, Véronique, Besson, Arnaud, Sarry, Jean-Emmanuel, Manenti, Stéphane, Didier, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245510/
https://ncbi.nlm.nih.gov/pubmed/32447346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0878-x
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi