Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy

Resistance of acute myeloid leukemia (AML) to therapeutic agents is frequent. Consequently, the mechanisms leading to this resistance must be understood and addressed. In this paper, we demonstrate that inhibition of deubiquitinylase USP7 significantly reduces cell proliferation in vitro and in vivo...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Leukemia
Главные авторы: Cartel, Maëlle, Mouchel, Pierre-Luc, Gotanègre, Mathilde, David, Laure, Bertoli, Sarah, Mansat-De Mas, Véronique, Besson, Arnaud, Sarry, Jean-Emmanuel, Manenti, Stéphane, Didier, Christine
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245510/
https://ncbi.nlm.nih.gov/pubmed/32447346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0878-x
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы