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The deubiquitinase USP10 regulates KLF4 stability and suppresses lung tumorigenesis
Krüppel-like factor 4 (KLF4), a key transcription factor, acts as a multifunctional player involved in the progression of numerous aggressive cancers. The proteasome-dependent pathway is one of the main modalities in controlling KLF4 abundance at a posttranslational level. Although some of the ubiqu...
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| Publicado en: | Cell Death Differ |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244734/ https://ncbi.nlm.nih.gov/pubmed/31748695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0458-7 |
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