The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog

Nanog is a master pluripotency factor of embryonic stem cells (ESCs). Stable expression of Nanog is essential to maintain the stemness of ESCs. However, Nanog is a short-lived protein and quickly degraded by the ubiquitin-dependent proteasome system. Here we report that the deubiquitinase USP21 inte...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Jin, Jiali, Liu, Jian, Chen, Cong, Liu, Zhenping, Jiang, Cong, Chu, Hongshang, Pan, Weijuan, Wang, Xinbo, Zhang, Lingqiang, Li, Bin, Jiang, Cizhong, Ge, Xin, Xie, Xin, Wang, Ping
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133637/
https://ncbi.nlm.nih.gov/pubmed/27886188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13594
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars