USP21 deubiquitylates Nanog to regulate protein stability and stem cell pluripotency

The homeobox transcription factor Nanog has a vital role in maintaining pluripotency and self-renewal of embryonic stem cells (ESCs). Stabilization of Nanog proteins is essential for ESCs. The ubiquitin–proteasome pathway mediated by E3 ubiquitin ligases and deubiquitylases is one of the key ways to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Liu, Xingyu, Yao, Yuying, Ding, Huiguo, Han, Chuanchun, Chen, Yuhan, Zhang, Yuan, Wang, Chanjuan, Zhang, Xin, Zhang, Yiling, Zhai, Yun, Wang, Ping, Wei, Wenyi, Zhang, Jing, Zhang, Lingqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661642/
https://ncbi.nlm.nih.gov/pubmed/29263902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sigtrans.2016.24
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados