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An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells
Interferon-α (IFNα), a type I interferon, is expressed in the islets of type 1 diabetic individuals, and its expression and signaling are regulated by T1D genetic risk variants and viral infections associated with T1D. We presently characterize human beta cell responses to IFNα by combining ATAC-seq...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244579/ https://ncbi.nlm.nih.gov/pubmed/32444635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16327-0 |
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