ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics

In contrast to the “Warburg effect” or aerobic glycolysis earlier generalized as a phenomenon in cancer cells, more and more recent evidence indicates that functional mitochondria are pivotal for ensuring the energy supply of cancer cells. Here, we report that cancer cells with reduced autophagy-rel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Liu, He, He, Zhaoyue, Germič, Nina, Ademi, Hyrijie, Frangež, Živa, Felser, Andrea, Peng, Shuang, Riether, Carsten, Djonov, Valentin, Nuoffer, Jean-Marc, Bovet, Cédric, Mlinarič-Raščan, Irena, Zlobec, Inti, Fiedler, Martin, Perren, Aurel, Simon, Hans-Uwe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244572/
https://ncbi.nlm.nih.gov/pubmed/31844253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0476-5
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg