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ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics

In contrast to the “Warburg effect” or aerobic glycolysis earlier generalized as a phenomenon in cancer cells, more and more recent evidence indicates that functional mitochondria are pivotal for ensuring the energy supply of cancer cells. Here, we report that cancer cells with reduced autophagy-rel...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Differ
Main Authors: Liu, He, He, Zhaoyue, Germič, Nina, Ademi, Hyrijie, Frangež, Živa, Felser, Andrea, Peng, Shuang, Riether, Carsten, Djonov, Valentin, Nuoffer, Jean-Marc, Bovet, Cédric, Mlinarič-Raščan, Irena, Zlobec, Inti, Fiedler, Martin, Perren, Aurel, Simon, Hans-Uwe
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244572/
https://ncbi.nlm.nih.gov/pubmed/31844253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0476-5
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