A carregar...

ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy

Anticancer drug therapy activates both molecular cell death and autophagy pathways. Here we show that even sublethal concentrations of DNA-damaging drugs, such as etoposide and cisplatin, induce the expression of autophagy-related protein 5 (ATG5), which is both necessary and sufficient for the subs...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Maskey, Dipak, Yousefi, Shida, Schmid, Inès, Zlobec, Inti, Perren, Aurel, Friis, Robert, Simon, Hans-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753548/
https://ncbi.nlm.nih.gov/pubmed/23945651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3130
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!