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Transient Reversal of RNA Polymerase II Active Site Closing Controls Fidelity of Transcription Elongation
To study fidelity of RNA polymerase II (Pol II), we analyzed properties of the 6-azauracil-sensitive and TFIIS-dependent E1103G mutant of rbp1 (rpo21), the gene encoding the catalytic subunit of Pol II in Saccharomyces cerevisiae. Using an in vivo retro-transposition-based transcription fidelity ass...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7243879/ https://ncbi.nlm.nih.gov/pubmed/18538654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.04.017 |
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