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De novo protein design, a retrospective

Proteins are molecular machines whose function depends on their ability to achieve complex folds with precisely defined structural and dynamic properties. The rational design of proteins from first-principles, or de novo, was once considered to be impossible, but today proteins with a variety of fol...

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Bibliographic Details
Published in:Q Rev Biophys
Main Authors: Korendovych, Ivan V., DeGrado, William F.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243446/
https://ncbi.nlm.nih.gov/pubmed/32041676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583519000131
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