Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients

INTRODUCTION: Antibiotic dosing in critically ill patients is challenging because their pharmacokinetics (PK) are altered and may change rapidly with disease progression. Standard dosing frequently leads to inadequate PK exposure. Therapeutic drug monitoring (TDM) offers a potential solution but req...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Roggeveen, Luca F., Guo, Tingjie, Driessen, Ronald H., Fleuren, Lucas M., Thoral, Patrick, van der Voort, Peter H. J., Girbes, Armand R. J., Bosman, Rob J., Elbers, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243359/
https://ncbi.nlm.nih.gov/pubmed/32499697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00646
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