Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock — rationale and design of a multicenter randomized controlled superiority trial

BACKGROUND: Antibiotic exposure is often inadequate in critically ill patients with severe sepsis or septic shock and this is associated with worse outcomes. Despite markedly altered and rapidly changing pharmacokinetics in these patients, guidelines and clinicians continue to rely on standard dosin...

詳細記述

保存先:
書誌詳細
出版年:Trials
主要な著者: Roggeveen, Luca F., Fleuren, Lucas M., Guo, Tingjie, Thoral, Patrick, de Grooth, Harm Jan, Swart, Eleonora L., Klausch, Thomas L. T., van der Voort, Peter H. J., Girbes, Armand R. J., Bosman, Rob J., Elbers, Paul W. G.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Study Protocol
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921499/
https://ncbi.nlm.nih.gov/pubmed/31852491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3911-5
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