External Evaluation of Population Pharmacokinetic Models of Vancomycin in Large Cohorts of Intensive Care Unit Patients

Dosing of vancomycin is often guided by therapeutic drug monitoring and population pharmacokinetic models in the intensive care unit (ICU). The validity of these models is crucial, as ICU patients have marked pharmacokinetic variability. Therefore, we set out to evaluate the predictive performance o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Guo, Tingjie, van Hest, Reinier M., Roggeveen, Luca F., Fleuren, Lucas M., Thoral, Patrick J., Bosman, Rob J., van der Voort, Peter H. J., Girbes, Armand R. J., Mathot, Ron A. A., Elbers, Paul W. G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496102/
https://ncbi.nlm.nih.gov/pubmed/30833424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02543-18
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