External Evaluation of Population Pharmacokinetic Models of Vancomycin in Large Cohorts of Intensive Care Unit Patients

Dosing of vancomycin is often guided by therapeutic drug monitoring and population pharmacokinetic models in the intensive care unit (ICU). The validity of these models is crucial, as ICU patients have marked pharmacokinetic variability. Therefore, we set out to evaluate the predictive performance o...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Guo, Tingjie, van Hest, Reinier M., Roggeveen, Luca F., Fleuren, Lucas M., Thoral, Patrick J., Bosman, Rob J., van der Voort, Peter H. J., Girbes, Armand R. J., Mathot, Ron A. A., Elbers, Paul W. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496102/
https://ncbi.nlm.nih.gov/pubmed/30833424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02543-18
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