Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients

INTRODUCTION: Antibiotic dosing in critically ill patients is challenging because their pharmacokinetics (PK) are altered and may change rapidly with disease progression. Standard dosing frequently leads to inadequate PK exposure. Therapeutic drug monitoring (TDM) offers a potential solution but req...

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Publicat a:Front Pharmacol
Autors principals: Roggeveen, Luca F., Guo, Tingjie, Driessen, Ronald H., Fleuren, Lucas M., Thoral, Patrick, van der Voort, Peter H. J., Girbes, Armand R. J., Bosman, Rob J., Elbers, Paul
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243359/
https://ncbi.nlm.nih.gov/pubmed/32499697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00646
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