Right Dose, Right Now: Development of AutoKinetics for Real Time Model Informed Precision Antibiotic Dosing Decision Support at the Bedside of Critically Ill Patients

INTRODUCTION: Antibiotic dosing in critically ill patients is challenging because their pharmacokinetics (PK) are altered and may change rapidly with disease progression. Standard dosing frequently leads to inadequate PK exposure. Therapeutic drug monitoring (TDM) offers a potential solution but req...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Roggeveen, Luca F., Guo, Tingjie, Driessen, Ronald H., Fleuren, Lucas M., Thoral, Patrick, van der Voort, Peter H. J., Girbes, Armand R. J., Bosman, Rob J., Elbers, Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243359/
https://ncbi.nlm.nih.gov/pubmed/32499697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00646
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