External Evaluation of Population Pharmacokinetic Models of Vancomycin in Large Cohorts of Intensive Care Unit Patients

Dosing of vancomycin is often guided by therapeutic drug monitoring and population pharmacokinetic models in the intensive care unit (ICU). The validity of these models is crucial, as ICU patients have marked pharmacokinetic variability. Therefore, we set out to evaluate the predictive performance o...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Guo, Tingjie, van Hest, Reinier M., Roggeveen, Luca F., Fleuren, Lucas M., Thoral, Patrick J., Bosman, Rob J., van der Voort, Peter H. J., Girbes, Armand R. J., Mathot, Ron A. A., Elbers, Paul W. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496102/
https://ncbi.nlm.nih.gov/pubmed/30833424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02543-18
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