Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock — rationale and design of a multicenter randomized controlled superiority trial

BACKGROUND: Antibiotic exposure is often inadequate in critically ill patients with severe sepsis or septic shock and this is associated with worse outcomes. Despite markedly altered and rapidly changing pharmacokinetics in these patients, guidelines and clinicians continue to rely on standard dosin...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Trials
Auteurs principaux: Roggeveen, Luca F., Fleuren, Lucas M., Guo, Tingjie, Thoral, Patrick, de Grooth, Harm Jan, Swart, Eleonora L., Klausch, Thomas L. T., van der Voort, Peter H. J., Girbes, Armand R. J., Bosman, Rob J., Elbers, Paul W. G.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Study Protocol
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921499/
https://ncbi.nlm.nih.gov/pubmed/31852491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3911-5
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires