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The C-terminal tails of the mitochondrial transcription factors Mtf1 and TFB2M are part of an autoinhibitory mechanism that regulates DNA binding

The structurally homologous Mtf1 and TFB2M proteins serve as transcription initiation factors of mitochondrial RNA polymerases in Saccharomyces cerevisiae and humans, respectively. These transcription factors directly interact with the nontemplate strand of the transcription bubble to drive promoter...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Basu, Urmimala, Mishra, Nandini, Farooqui, Mohammed, Shen, Jiayu, Johnson, Laura C., Patel, Smita S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242694/
https://ncbi.nlm.nih.gov/pubmed/32241911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013338
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